亜紗 本店 (Asa Honten)

Steps from the Sakuramachi tram stop, Asa Honten is the flagship of Nagasaki’s well-known Asa izakaya group, serving creative seafood-forward dishes late into the night, seven days a week. The relaxed room mixes counter, tatami, and sunken-kotatsu seating.

Closures are irregular rather than a fixed weekly day off — best to confirm before visiting. A repeat Hyakumeiten selection, it’s a dependable late-night option in central Nagasaki.